Post-exposure prophylaxis for Middle East respiratory syndrome in healthcare workers
Identifieur interne : 000854 ( Main/Exploration ); précédent : 000853; suivant : 000855Post-exposure prophylaxis for Middle East respiratory syndrome in healthcare workers
Auteurs : S. Y. Park [Corée du Sud] ; J. S. Lee [Corée du Sud] ; J. S. Son [Corée du Sud] ; J. H. Ko [Corée du Sud] ; K. R. Peck [Corée du Sud] ; Y. Jung [Corée du Sud] ; H. J. Woo [Corée du Sud] ; Y. S. Joo [Corée du Sud] ; J. S. Eom [Corée du Sud] ; H. Shi [Corée du Sud]Source :
- The Journal of Hospital Infection [ 0195-6701 ] ; 2018.
Descripteurs français
- KwdFr :
- Adulte, Antiviraux (administration et posologie), Antiviraux (effets indésirables), Effets secondaires indésirables des médicaments (anatomopathologie), Effets secondaires indésirables des médicaments (épidémiologie), Femelle, Humains, Incidence, Infections à coronavirus (), Jeune adulte, Lopinavir (administration et posologie), Lopinavir (effets indésirables), Mâle, Personnel de santé, Prophylaxie après exposition (), Ribavirine (administration et posologie), Ribavirine (effets indésirables), Ritonavir (administration et posologie), Ritonavir (effets indésirables), Sujet âgé, Études rétrospectives.
- MESH :
- administration et posologie : Antiviraux, Lopinavir, Ribavirine, Ritonavir.
- anatomopathologie : Effets secondaires indésirables des médicaments.
- effets indésirables : Antiviraux, Lopinavir, Ribavirine, Ritonavir.
- épidémiologie : Effets secondaires indésirables des médicaments.
- Adulte, Femelle, Humains, Incidence, Infections à coronavirus, Jeune adulte, Mâle, Personnel de santé, Prophylaxie après exposition, Sujet âgé, Études rétrospectives.
English descriptors
- KwdEn :
- Adult, Aged, Antiviral Agents (administration & dosage), Antiviral Agents (adverse effects), Coronavirus Infections (prevention & control), Drug-Related Side Effects and Adverse Reactions (epidemiology), Drug-Related Side Effects and Adverse Reactions (pathology), Female, Health Personnel, Humans, Incidence, Lopinavir (administration & dosage), Lopinavir (adverse effects), Male, Post-Exposure Prophylaxis (methods), Retrospective Studies, Ribavirin (administration & dosage), Ribavirin (adverse effects), Ritonavir (administration & dosage), Ritonavir (adverse effects), Young Adult.
- MESH :
- chemical , administration & dosage : Antiviral Agents, Lopinavir, Ribavirin, Ritonavir.
- chemical , adverse effects : Antiviral Agents, Lopinavir, Ribavirin, Ritonavir.
- epidemiology : Drug-Related Side Effects and Adverse Reactions.
- methods : Post-Exposure Prophylaxis.
- pathology : Drug-Related Side Effects and Adverse Reactions.
- prevention & control : Coronavirus Infections.
- Adult, Aged, Female, Health Personnel, Humans, Incidence, Male, Retrospective Studies, Young Adult.
Abstract
An effective post-exposure prophylaxis (PEP) strategy may limit the spread of infection. However, there is no consensus regarding PEP for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. This study assessed the efficacy of ribavirin and lopinavir/ritonavir as PEP for healthcare workers (HCWs) exposed to patients with severe MERS-CoV pre-isolation pneumonia. The safety of the PEP regimen was assessed. HCWs with high-risk exposure to MERS-CoV pre-isolation pneumonia were retrospectively enrolled. HCWs who received PEP therapy were classified into the PEP group. PEP therapy was associated with a 40% decrease in the risk of infection. There were no severe adverse events during PEP therapy.
Url:
DOI: 10.1016/j.jhin.2018.09.005
PubMed: 30240813
PubMed Central: 7114948
Affiliations:
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Joo</name><affiliation wicri:level="1"><nlm:aff id="aff6">Department of Occupational and Environmental Medicine, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Gyeonggi, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Occupational and Environmental Medicine, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Gyeonggi</wicri:regionArea><wicri:noRegion>Gyeonggi</wicri:noRegion></affiliation></author><author><name sortKey="Eom, J S" sort="Eom, J S" uniqKey="Eom J" first="J. S." last="Eom">J. S. 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Y." last="Park">S. Y. Park</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Infectious Diseases, Kangdong Sacred Heart Hospital, Hallym University School of Medicine, Seoul, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Kangdong Sacred Heart Hospital, Hallym University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lee, J S" sort="Lee, J S" uniqKey="Lee J" first="J. S." last="Lee">J. S. 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Son</name><affiliation wicri:level="3"><nlm:aff id="aff2">Division of Infectious Diseases, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Ko, J H" sort="Ko, J H" uniqKey="Ko J" first="J. H." last="Ko">J. H. Ko</name><affiliation wicri:level="3"><nlm:aff id="aff3">Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Peck, K R" sort="Peck, K R" uniqKey="Peck K" first="K. R." last="Peck">K. R. Peck</name><affiliation wicri:level="3"><nlm:aff id="aff3">Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Jung, Y" sort="Jung, Y" uniqKey="Jung Y" first="Y." last="Jung">Y. Jung</name><affiliation wicri:level="1"><nlm:aff id="aff4">Division of Infectious Diseases, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Gyeonggi, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Gyeonggi</wicri:regionArea><wicri:noRegion>Gyeonggi</wicri:noRegion></affiliation></author><author><name sortKey="Woo, H J" sort="Woo, H J" uniqKey="Woo H" first="H. J." last="Woo">H. J. Woo</name><affiliation wicri:level="1"><nlm:aff id="aff5">Division of Infectious Diseases, Dongtan Sacred Heart Hospital, Hallym University School of Medicine, Hwasung, Gyeonggi, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Dongtan Sacred Heart Hospital, Hallym University School of Medicine, Hwasung, Gyeonggi</wicri:regionArea><wicri:noRegion>Gyeonggi</wicri:noRegion></affiliation></author><author><name sortKey="Joo, Y S" sort="Joo, Y S" uniqKey="Joo Y" first="Y. S." last="Joo">Y. S. Joo</name><affiliation wicri:level="1"><nlm:aff id="aff6">Department of Occupational and Environmental Medicine, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Gyeonggi, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Occupational and Environmental Medicine, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Gyeonggi</wicri:regionArea><wicri:noRegion>Gyeonggi</wicri:noRegion></affiliation></author><author><name sortKey="Eom, J S" sort="Eom, J S" uniqKey="Eom J" first="J. S." last="Eom">J. S. Eom</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Infectious Diseases, Kangdong Sacred Heart Hospital, Hallym University School of Medicine, Seoul, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Kangdong Sacred Heart Hospital, Hallym University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Shi, H" sort="Shi, H" uniqKey="Shi H" first="H." last="Shi">H. Shi</name><affiliation wicri:level="3"><nlm:aff id="aff1">Division of Infectious Diseases, Kangdong Sacred Heart Hospital, Hallym University School of Medicine, Seoul, South Korea</nlm:aff><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Infectious Diseases, Kangdong Sacred Heart Hospital, Hallym University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author></analytic><series><title level="j">The Journal of Hospital Infection</title><idno type="ISSN">0195-6701</idno><idno type="eISSN">1532-2939</idno><imprint><date when="2018">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Antiviral Agents (administration & dosage)</term><term>Antiviral Agents (adverse effects)</term><term>Coronavirus Infections (prevention & control)</term><term>Drug-Related Side Effects and Adverse Reactions (epidemiology)</term><term>Drug-Related Side Effects and Adverse Reactions (pathology)</term><term>Female</term><term>Health Personnel</term><term>Humans</term><term>Incidence</term><term>Lopinavir (administration & dosage)</term><term>Lopinavir (adverse effects)</term><term>Male</term><term>Post-Exposure Prophylaxis (methods)</term><term>Retrospective Studies</term><term>Ribavirin (administration & dosage)</term><term>Ribavirin (adverse effects)</term><term>Ritonavir (administration & dosage)</term><term>Ritonavir (adverse effects)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Antiviraux (administration et posologie)</term><term>Antiviraux (effets indésirables)</term><term>Effets secondaires indésirables des médicaments (anatomopathologie)</term><term>Effets secondaires indésirables des médicaments (épidémiologie)</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Infections à coronavirus ()</term><term>Jeune adulte</term><term>Lopinavir (administration et posologie)</term><term>Lopinavir (effets indésirables)</term><term>Mâle</term><term>Personnel de santé</term><term>Prophylaxie après exposition ()</term><term>Ribavirine (administration et posologie)</term><term>Ribavirine (effets indésirables)</term><term>Ritonavir (administration et posologie)</term><term>Ritonavir (effets indésirables)</term><term>Sujet âgé</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antiviral Agents</term><term>Lopinavir</term><term>Ribavirin</term><term>Ritonavir</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiviral Agents</term><term>Lopinavir</term><term>Ribavirin</term><term>Ritonavir</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Antiviraux</term><term>Lopinavir</term><term>Ribavirine</term><term>Ritonavir</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Effets secondaires indésirables des médicaments</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Antiviraux</term><term>Lopinavir</term><term>Ribavirine</term><term>Ritonavir</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Drug-Related Side Effects and Adverse Reactions</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Post-Exposure Prophylaxis</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Drug-Related Side Effects and Adverse Reactions</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Effets secondaires indésirables des médicaments</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Health Personnel</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Retrospective Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Infections à coronavirus</term><term>Jeune adulte</term><term>Mâle</term><term>Personnel de santé</term><term>Prophylaxie après exposition</term><term>Sujet âgé</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>An effective post-exposure prophylaxis (PEP) strategy may limit the spread of infection. However, there is no consensus regarding PEP for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. This study assessed the efficacy of ribavirin and lopinavir/ritonavir as PEP for healthcare workers (HCWs) exposed to patients with severe MERS-CoV pre-isolation pneumonia. The safety of the PEP regimen was assessed. HCWs with high-risk exposure to MERS-CoV pre-isolation pneumonia were retrospectively enrolled. HCWs who received PEP therapy were classified into the PEP group. PEP therapy was associated with a 40% decrease in the risk of infection. There were no severe adverse events during PEP therapy.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A. McGeer</name></author><author><name sortKey="Perl, T M" uniqKey="Perl T">T.M. Perl</name></author><author><name sortKey="Price, C S" uniqKey="Price C">C.S. Price</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A.A. Al Rabeeah</name></author><author><name sortKey="Cummings, D A" uniqKey="Cummings D">D.A. Cummings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, S G" uniqKey="Kim S">S.G. Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Muller</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Al Masri, M" uniqKey="Al Masri M">M. Al-Masri</name></author><author><name sortKey="Turkestani, A" uniqKey="Turkestani A">A. Turkestani</name></author><author><name sortKey="Ritz, D" uniqKey="Ritz D">D. Ritz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Centers For Disease Control And Prevention" uniqKey="Centers For Disease Control And Prevention">Centers for Disease Control and Prevention</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hunter, J C" uniqKey="Hunter J">J.C. Hunter</name></author><author><name sortKey="Nguyen, D" uniqKey="Nguyen D">D. Nguyen</name></author><author><name sortKey="Aden, B" uniqKey="Aden B">B. Aden</name></author><author><name sortKey="Al Bandar, Z" uniqKey="Al Bandar Z">Z. Al Bandar</name></author><author><name sortKey="Al Dhaheri, W" uniqKey="Al Dhaheri W">W. Al Dhaheri</name></author><author><name sortKey="Abu Elkheir, K" uniqKey="Abu Elkheir K">K. Abu Elkheir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, J F" uniqKey="Chan J">J.F. Chan</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Kao, R Y" uniqKey="Kao R">R.Y. Kao</name></author><author><name sortKey="To, K K" uniqKey="To K">K.K. To</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Li, C P" uniqKey="Li C">C.P. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Wilde, A H" uniqKey="De Wilde A">A.H. de Wilde</name></author><author><name sortKey="Jochmans, D" uniqKey="Jochmans D">D. Jochmans</name></author><author><name sortKey="Posthuma, C C" uniqKey="Posthuma C">C.C. Posthuma</name></author><author><name sortKey="Zevenhoven Dobbe, J C" uniqKey="Zevenhoven Dobbe J">J.C. Zevenhoven-Dobbe</name></author><author><name sortKey="Van Nieuwkoop, S" uniqKey="Van Nieuwkoop S">S. van Nieuwkoop</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T.M. Bestebroer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spanakis, N" uniqKey="Spanakis N">N. Spanakis</name></author><author><name sortKey="Tsiodras, S" uniqKey="Tsiodras S">S. Tsiodras</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author><author><name sortKey="Raj, V S" uniqKey="Raj V">V.S. Raj</name></author><author><name sortKey="Pontikis, K" uniqKey="Pontikis K">K. Pontikis</name></author><author><name sortKey="Koutsoukou, A" uniqKey="Koutsoukou A">A. Koutsoukou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Omrani, A S" uniqKey="Omrani A">A.S. Omrani</name></author><author><name sortKey="Saad, M M" uniqKey="Saad M">M.M. Saad</name></author><author><name sortKey="Baig, K" uniqKey="Baig K">K. Baig</name></author><author><name sortKey="Bahloul, A" uniqKey="Bahloul A">A. Bahloul</name></author><author><name sortKey="Abdul Matin, M" uniqKey="Abdul Matin M">M. Abdul-Matin</name></author><author><name sortKey="Alaidaroos, A Y" uniqKey="Alaidaroos A">A.Y. Alaidaroos</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Corée du Sud</li></country><region><li>Région capitale de Séoul</li></region><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Park, S Y" sort="Park, S Y" uniqKey="Park S" first="S. Y." last="Park">S. Y. Park</name></region><name sortKey="Eom, J S" sort="Eom, J S" uniqKey="Eom J" first="J. S." last="Eom">J. S. Eom</name><name sortKey="Joo, Y S" sort="Joo, Y S" uniqKey="Joo Y" first="Y. S." last="Joo">Y. S. Joo</name><name sortKey="Jung, Y" sort="Jung, Y" uniqKey="Jung Y" first="Y." last="Jung">Y. Jung</name><name sortKey="Ko, J H" sort="Ko, J H" uniqKey="Ko J" first="J. H." last="Ko">J. H. Ko</name><name sortKey="Lee, J S" sort="Lee, J S" uniqKey="Lee J" first="J. S." last="Lee">J. S. Lee</name><name sortKey="Peck, K R" sort="Peck, K R" uniqKey="Peck K" first="K. R." last="Peck">K. R. Peck</name><name sortKey="Shi, H" sort="Shi, H" uniqKey="Shi H" first="H." last="Shi">H. Shi</name><name sortKey="Son, J S" sort="Son, J S" uniqKey="Son J" first="J. S." last="Son">J. S. Son</name><name sortKey="Woo, H J" sort="Woo, H J" uniqKey="Woo H" first="H. J." last="Woo">H. J. Woo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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